Remission in cushing disease with cabergoline

Remission with Cabergoline in Adolescent Boys with Cushing’s Disease

Cabergoline is a long-acting dopamine receptor agonist used for treatment of patients with uncured Cushing's disease (CD) and, as a first-line treatment, was used in only limited numbers of patients. This report presents two adolescent boys with CD who were treated with cabergoline. Two adolescent boys with clinical and laboratory findings of CD are presented. No pituitary adenoma was detected ...

Valvular Heart Disease in Patients with Prolactinomas on Cabergoline Treatment

Dopamine agonists are the first line treatment of prolactinomas and Parkinson’s disease. Has shown an association between the use of high doses of ergot dopamine agonists, cabergoline and pergolide, and development of clinically significant (moderate to severe) heart valve regurgitation, valvular thickening and retraction in patients with Parkinson’s disease [1,2]. Because of this, he has appea...

Pasireotide alone or with cabergoline and ketoconazole in Cushing's disease.

Dilated Cardiomyopathy Revealing Cushing Disease

Cardiovascular impairments are frequent in Cushing’s syndrome and the hypercortisolism can result in cardiac structural and functional changes that lead in rare cases to dilated cardiomyopathy (DCM). Such cardiac impairment may be reversible in response to a eucortisolaemic state. A 43-year-old man with a medical past of hypertension and history of smoking presented to the emergency department ...

Cushing, cortisol, and cardiovascular disease.

Cushing's syndrome of glucocorticoid excess is named after the eminent Boston neurosurgeon Harvey W. Cushing (1869-1939). The recognition that glucocorticoid excess produces hypertension led to examination of the role of cortisol in essential hypertension, but it is only over the last decade that evidence has emerged to support the concept. Despite the widespread assumption that cortisol raises...